Skin Boosters / Mesotherapy (Rejuran, Celexo, Re2O)

Advanced Skin Renewal For Long-Lasting Radiance

Skin boosters and mesotherapy deliver targeted nutrients and regenerative ingredients directly into the skin to support hydration, collagen production, and skin rejuvenation. Unlike traditional fillers, these treatments focus on improving skin quality, texture, and natural radiance.

Deep Skin Hydration

Enhances moisture levels to create smoother, healthier, and more radiant-looking skin.

Collagen Support

Helps stimulate skin renewal for improved firmness, elasticity, and texture.

Natural Enhancement

Improves overall skin quality while maintaining your natural facial appearance.

Personalized Solutions For Healthier Skin

At AGEREFINE CLINIC, we offer advanced skin rejuvenation options selected according to your skin concerns and aesthetic goals.

Rejuran

Rejuran utilises a unique ingredient – polynucleotides (PN) derived from salmon DNA. Salmon DNA is known for its superior histocompatibility to human tissue, facilitating easy absorption and promoting the regenerative process. PNs are highly potent, long-chain DNA molecules that stimulate the process of cell regeneration, collagen production, and tissue repair, resulting in improved skin elasticity, texture, and hydration.

  • Supports skin repair
  • Improves texture
  • Enhances skin quality

Celexo

Clinical-grade, exosome-based skincare products designed to enhance skin regeneration, repair, and rejuvenation

  • Skin Barrier Repair 

  • Hydration & Smoothness

  • Anti-Inflammaging

  • Firming & Texture Refinement 

Re2O

A next-generation ECM skin booster designed to replenish collagen and elastin for firmer, smoother, healthier-looking skin.

  • Structural Rebuilding: Directly delivers ECM scaffold components to support the skin’s underlying structure—not just surface hydration or indirect stimulation.
  • Pore & Texture Refinement: Clinically reported to reduce the appearance of pores by approximately 17%–26% while improving skin texture and density.
  • Elasticity & Fine Lines: Supports type I and type III collagen to improve firmness, elasticity, fine lines, and under-eye smoothness.

Refresh Your Skin With Minimal Downtime

Skin booster treatments are designed to enhance your skin gradually, improving hydration, texture, and radiance while maintaining a natural appearance.

Treatment Time

Quick sessions designed for your convenience.

Recovery

Temporary redness or sensitivity may occur.

Results

Skin improvements develop progressively after treatment.

Healthy Skin Starts With The Right Support

Skin boosters provide a powerful approach to improving skin quality by working beneath the surface to enhance hydration, renewal, and overall appearance.

Improved Hydration

Brighter Complexion

Better Skin Texture

Collagen Support

Minimal Downtime

Customized Care

BOTOX® vs. XEOMIN®

Wrinkle Relaxing • Facial Refinement • Muscle Slimming • Therapeutic Treatment
At AgeRefine Clinic, BOTOX® and XEOMIN® treatments go beyond wrinkle reduction.
These injectable neuromodulators temporarily reduce targeted muscle activity and can be used to create a smoother, softer and more balanced appearance. Botulinum toxin also has established medical applications and may be used for certain therapeutic concerns.
Every treatment is customized according to your anatomy, muscle strength, concerns and desired results.

What Can We Treat?

FACE

  • Smooth Wrinkles & Refine Facial Contours
  • Forehead Lines
    Softens horizontal lines created when raising the eyebrows.
  • Frown Lines / “11 Lines”
    Reduces the vertical lines that develop between the eyebrows.
  • Crow’s Feet
    Softens expression lines around the outer corners of the eyes.
  • Bunny Lines
    Reduces fine expression lines along the sides of the nose.
  • Lip Flip
    Gently relaxes the muscle around the upper lip, allowing slightly more of the lip to show when smiling.
  • Gummy Smile
    Helps reduce excessive upper-lip elevation when smiling.
  • Chin Dimpling
    Relaxes an overactive chin muscle to create a smoother appearance.
  • Downturned Mouth Corners
    Strategic treatment may help soften the downward pull at the corners of the mouth.
  • Jawline / Masseter Treatment
    Relaxing enlarged masseter muscles may create a softer, slimmer lower-face appearance over time.
  • Neck Bands
    Targeted treatment can soften prominent platysmal bands and improve the appearance of the neck.

BODY CONTOURING

Slim the Appearance of Overdeveloped Muscles

Botulinum toxin can also be strategically injected into selected body muscles to temporarily reduce muscle activity and, over time, decrease the prominence of an enlarged muscle.

  • Shoulder Slimming / TrapTox

Treatment of prominent trapezius muscles may help create the appearance of:

A softer shoulder line

A more elongated-looking neck

Less bulky upper shoulders

A more delicate neck-to-shoulder contour

This treatment is sometimes referred to as TrapTox or “Barbie Botox.”

  • Calf Slimming

For patients whose calves appear larger primarily because of prominent calf muscles, targeted botulinum toxin treatment may gradually reduce muscle prominence.

The goal is to create a slimmer, more streamlined appearance of the lower legs without surgery.

Shoulder and calf slimming with botulinum toxin are off-label aesthetic uses in the United States. A consultation is necessary to determine whether muscle size—not fat or another cause—is responsible for the area of concern.

HEADACHE & THERAPEUTIC TREATMENT

BOTOX® is FDA-approved for the prevention of headaches in adults with chronic migraine.

Treatment for chronic migraine is different from cosmetic BOTOX®. It involves a specific injection protocol across multiple areas of the head and neck and should only be performed when medically appropriate.

Not every type of headache is treated with botulinum toxin. A medical evaluation is necessary to determine whether you are an appropriate candidate.

Other Muscle-Related Concerns

Depending on your individual evaluation and clinical indication, botulinum toxin may also be considered for certain muscle-related concerns.

Some therapeutic applications may be off-label and will be discussed with you before treatment.

BOTOX® or XEOMIN®?

What’s the Difference?

Both are prescription botulinum toxin type A products that temporarily reduce targeted muscle activity, but they are different formulations and their units are not interchangeable.

XEOMIN® is manufactured without the accessory proteins found in some other botulinum toxin formulations.

It provides another option for patients seeking precise, customized neuromodulator treatment.

Which Should I Choose?

You don’t have to decide before your appointment.

At AgeRefine Clinic, we evaluate your anatomy, muscle movement, treatment history and goals before recommending the appropriate product and dose.

Results in 3-7 Days, Lasts 3-4 Months

Filler vs. Sculptra®

Facial aging isn't only about wrinkles.

Over time, we naturally experience changes in collagen, facial volume, skin thickness, bone structure, and facial support. These changes can lead to hollowing, deeper folds, loss of definition, and an overall tired appearance.

At AgeRefine Clinic, we offer dermal fillers and Sculptra® as two different approaches to facial rejuvenation.

Dermal Fillers → Restore volume and enhance facial contours with more immediate results.

Sculptra® → Stimulates your own collagen production for gradual, natural-looking rejuvenation.

The right treatment depends on your facial anatomy, degree of volume loss, skin quality, and aesthetic goals.

Restore Volume. Refine Your Features.

Dermal fillers are injectable treatments designed to restore lost volume, soften certain folds and wrinkles, and enhance facial contours.

Many commonly used fillers are made with hyaluronic acid (HA), a substance naturally present in the skin that helps attract and retain moisture.

Results are typically visible immediately, although swelling and the final settling of the product can temporarily affect the appearance after treatment.

What Can Dermal Fillers Treat?

Cheeks & Midface

Restore age-related volume loss and enhance cheek structure for a more balanced facial contour.

Lips

Enhance lip shape, definition, symmetry, and volume while maintaining natural proportions.

Chin

Improve chin projection and contour to create greater balance between the upper and lower face.

Jawline

Enhance definition and improve the appearance of the lower facial contour.

Nasolabial Folds

Soften deeper folds extending from the sides of the nose toward the corners of the mouth.

Marionette Lines

Improve lines and folds extending downward from the corners of the mouth.

Facial Hollows & Volume Loss

Sculptra®

Don't Just Replace Volume. Rebuild Collagen.

Sculptra® works differently from traditional dermal filler.

Instead of simply placing gel into an area to create immediate volume, Sculptra contains poly-L-lactic acid (PLLA), a biocompatible material that stimulates your body’s own collagen production.

The result develops gradually as new collagen forms.

Rather than looking suddenly “filled,” your appearance can become progressively refreshed over the following weeks and months.

What Can Sculptra® Improve?

Sculptra may be used to address:

  • Facial volume loss
  • Cheek and midface hollowing
  • Certain facial wrinkles and folds
  • Loss of facial structure and support
  • Age-related collagen depletion
  • Overall facial rejuvenation

The goal is a gradual restoration of facial structure and a naturally refreshed appearance.

Filler vs. Sculptra®

What's the Difference?

Choose Dermal Filler When You Want:

More immediate correction

Filler can be ideal when the goal is to restore volume or precisely enhance the shape and contour of a specific facial feature.

Best suited for:
Lips • Cheeks • Chin • Jawline • Selected folds and areas of volume loss

Choose Sculptra® When You Want:

Gradual collagen regeneration

Sculptra may be ideal for patients experiencing more generalized facial volume loss and collagen depletion who prefer progressive, natural-looking improvement.

Best suited for:
Facial volume loss • Collagen loss • Cheek/midface rejuvenation • Broader facial restoration

Sometimes, the Best Approach Is Both

Filler and Sculptra don’t necessarily compete with one another.

They address aging in different ways.

A customized treatment plan may use Sculptra to support gradual collagen restoration while strategically using dermal filler for areas that benefit from precise contouring or volume replacement.

Why Does Collagen Matter?

Collagen provides much of the skin’s structure, firmness, and support.

Natural collagen production decreases with age, contributing to:

Thinner skin • Loss of elasticity • Facial hollowing • Wrinkles • Reduced structural support

Sculptra works by stimulating collagen production rather than relying solely on an injectable gel to create volume.

Because this process takes time, Sculptra results appear progressively.

What to Expect With Dermal Filler

Treatment Time
Usually approximately 30–60 minutes depending on the treatment area.

Results
Volume and contour changes are generally visible immediately, with the appearance continuing to settle as temporary swelling resolves.

Downtime
Bruising, swelling, redness, tenderness, or temporary asymmetry may occur following injections.

Longevity
How long filler lasts depends on the product, treatment area, amount used, metabolism, and individual patient factors.

What to Expect With Sculptra®

Treatment Time
Typically approximately 30–60 minutes.

Results
Sculptra works gradually. Collagen remodeling develops over the weeks and months following treatment.

Number of Treatments
A series of treatments may be recommended depending on your age, degree of volume loss, and treatment goals.

Longevity
Results can be long-lasting, although individual response varies and maintenance treatment may be recommended.

The AgeRefine Approach

Facial Rejuvenation Should Look Like You

More filler isn’t always better.

At AgeRefine Clinic, treatment begins with an assessment of your entire face—not simply the wrinkle or hollow that brought you in.

We consider your:

Facial proportions • Bone structure • Volume distribution • Skin quality • Facial movement • Signs of collagen loss

From there, we determine whether dermal filler, Sculptra®, another treatment, or a combination approach is most appropriate.

Our goal is not to change your features.

It is to help restore balance, structure, and a naturally refreshed appearance.

Filler or Sculptra®?

You Don’t Have to Decide Before Your Appointment.

During your consultation, we’ll evaluate your facial anatomy, skin quality, volume loss, and goals and explain which approach may be most appropriate for you.

Immediate Volume → Dermal Filler

Gradual Collagen Stimulation → Sculptra®

Comprehensive Rejuvenation → Personalized Combination Treatment

Refined. Balanced. Naturally You.

Schedule your consultation at AgeRefine Clinic.

Skin Booster Treatment FAQs

Skin boosters are injectable treatments designed to improve hydration, elasticity, and overall skin quality.

No. Skin boosters focus on improving skin health and hydration, while fillers are designed primarily to restore volume.

Most patients experience minimal discomfort. Comfort measures may be used during treatment.

The number of sessions depends on your skin condition and goals. Your provider will recommend a personalized plan.

Results vary depending on the treatment but improvements typically appear gradually as skin quality improves.

Your Journey To Healthier Skin

01

Consultation

Discuss your goals, concerns, and desired outcomes.

02

Facial Assessment

Evaluate your facial muscles and determine treatment areas.

03

Treatment Session

Receive a customized treatment recommendation.

04

Follow-Up Care

Receive guidance to maintain and optimize your results.

Achieve A Naturally Radiant Complexion

Book your consultation at AGEREFINE CLINIC and discover a personalized skin rejuvenation plan designed to restore hydration, texture, and confidence.